News https://www.lupop.lu.se/ en Multigenerational health research using population-based linked databases: an international review https://www.lupop.lu.se/article/multigenerational-health-research-using-population-based-linked-databases-international-review This review provides important insights about the benefits and challenges of using routinely-collected, population-based linked databases for conducting population-based… Wed, 24 Nov 2021 10:20:01 +0100 29b47918-3ff6-40d1-b8f1-6f2354e103da Job opportunity: Associate Researcher in Epidemiological Surveillance Studies https://www.lupop.lu.se/article/job-opportunity-associate-researcher-epidemiological-surveillance-studies The research group of Epidemiology and Population Studies (EPI@Lund), lead by professor Jonas Björk, is looking for an associate researcher in Epidemiology, Public Health, Data… Wed, 24 Nov 2021 08:33:08 +0100 66959976-b3ff-45fb-8158-6fb2358393ce Data Sources That Enumerate People Experiencing Homelessness in the United States: Opportunities and Challenges for Epidemiologic Research https://www.lupop.lu.se/article/data-sources-enumerate-people-experiencing-homelessness-united-states-opportunities-and-challenges Here, we outline 3 federal, publicly available data sources for estimating the number of people experiencing homelessness in the United States. We describe the appropriate uses… Tue, 23 Nov 2021 11:49:43 +0100 d260be16-5b4d-49ea-9875-d4644d285fe9 Assortativity and Bias in Epidemiologic Studies of Contagious Outcomes: A Simulated Example in the Context of Vaccination https://www.lupop.lu.se/article/assortativity-and-bias-epidemiologic-studies-contagious-outcomes-simulated-example-context Assortativity is the tendency of individuals connected in a network to share traits and behaviors. Through simulations, we demonstrated the potential for bias resulting from… Mon, 22 Nov 2021 10:20:01 +0100 78c13a63-adc9-410e-b3a4-f545b1f9a242 Concordance among Swedish, German, Danish, and UK EQ-5D-3L Value Sets: Analyses of Patient-Reported Outcomes in the Swedish Hip Arthroplasty Register https://www.lupop.lu.se/article/concordance-among-swedish-german-danish-and-uk-eq-5d-3l-value-sets-analyses-patient-reported Among THR patients value sets based on the same method and perspective, a direct transfer of results across countries could be meaningful. In cases of differences in methods and… Sun, 21 Nov 2021 10:19:50 +0100 441ae569-cf3d-49a6-b8d3-1d68008ac948 A Prospective Stroke Register in Sierra Leone: Demographics, Stroke Type, Stroke Care and Hospital Outcomes https://www.lupop.lu.se/article/prospective-stroke-register-sierra-leone-demographics-stroke-type-stroke-care-and-hospital-outcomes Stroke is the second most common cause of adult death in Africa. This study reports the demographics, stroke types, stroke care and hospital outcomes for stroke in Freetown,… Sat, 20 Nov 2021 10:19:42 +0100 5ee2902e-8362-4933-a618-b459c576d743 Comprehensive registry of esophageal cancer in Japan, 2014 https://www.lupop.lu.se/article/comprehensive-registry-esophageal-cancer-japan-2014 The registration committee for esophageal cancer in the Japan Esophageal Society (JES) has collected the patients' characteristics, treatment, and outcomes annually. Fri, 19 Nov 2021 10:19:53 +0100 4e06fa1f-36c8-48df-a9fb-7ff2e1117ca0 Datum klara för Vetenskapsrådets utlysningar 2022 https://www.lupop.lu.se/article/datum-klara-vetenskapsradets-utlysningar-2022 Thu, 18 Nov 2021 14:06:39 +0100 5ab9c3ec-91ef-4dea-b1d6-bb9600534bc2 The effect of adjustment to register-based and questionnaire-based covariates on the association between air pollution and cardiometabolic disease https://www.lupop.lu.se/article/effect-adjustment-register-based-and-questionnaire-based-covariates-association-between-air Our findings suggest that in studies of air pollution and cardiometabolic disease, which use an adjustment strategy with a broad range of register-based socioeconomic variables,… Thu, 18 Nov 2021 10:19:43 +0100 32d6b58a-b32b-4103-9c0f-b87d2583c1f2 RESTORE: A Prospective Multinational Registry of Patients with Genetically Confirmed Spinal Muscular Atrophy - Rationale and Study Design https://www.lupop.lu.se/article/restore-prospective-multinational-registry-patients-genetically-confirmed-spinal-muscular-atrophy This registry will assess outcomes in patients with genetically confirmed SMA and provide information on the effectiveness and long-term safety of approved and emerging treatments. Wed, 17 Nov 2021 10:19:45 +0100 d3973338-685c-40d7-b0c1-da9785861313 Looking beyond the numbers: quality assurance procedures in the Global Network for Women’s and Children’s Health Research Maternal Newborn Health Registry https://www.lupop.lu.se/article/looking-beyond-numbers-quality-assurance-procedures-global-network-womens-and-childrens-health We developed standardized QA processes for training, certification and supervision of the MNHR, a multisite research registry. It is expected that these activities, together with… Tue, 16 Nov 2021 10:20:13 +0100 af4703d7-2276-4602-92e6-0ef60df2abf3 Job opportunity: Senior Lecturer in epidemiology with focus on environmental health risk assessment at KI https://www.lupop.lu.se/article/job-opportunity-senior-lecturer-epidemiology-focus-environmental-health-risk-assessment-ki The senior lecturer in epidemiology with a focus on research must, in addition to conducting high-quality epidemiological research primarily concerning the etiology of allergic… Tue, 16 Nov 2021 09:29:35 +0100 dbb32769-474e-4d33-b27d-a81436e857ef Establishing an institutional reverse total shoulder arthroplasty registry https://www.lupop.lu.se/article/establishing-institutional-reverse-total-shoulder-arthroplasty-registry A well-managed institutional arthroplasty registry, including structured clinical and radiological follow-up assessments, offers the opportunity for high-quality long-term patient… Mon, 15 Nov 2021 10:20:17 +0100 c806cf55-7f78-41fc-87bd-45324de426ee Accuracy of injury coding in a trauma registry https://www.lupop.lu.se/article/accuracy-injury-coding-trauma-registry The overall accuracy of data held in the New Zealand Trauma Registry (NZTR) is suitable for quality improvement and benchmarking purposes, but more work is needed to improve the… Sun, 14 Nov 2021 10:20:02 +0100 235af671-b570-402b-be8b-298a4c0d879a Utilization of a National Registry to influence opioid prescribing behavior after hernia repair https://www.lupop.lu.se/article/utilization-national-registry-influence-opioid-prescribing-behavior-after-hernia-repair Despite progress toward curtailing opioid prescribing, physicians are often slow to adopt new prescribing practices. Using the Abdominal Core Health Quality Collaborative (ACHQC… Sat, 13 Nov 2021 10:19:58 +0100 0809c7aa-cff5-4c6e-9d04-0a002499bc05 Replication of Oncology Randomized Trial Results using Swedish Registry Real World-Data: A Feasibility Study https://www.lupop.lu.se/article/replication-oncology-randomized-trial-results-using-swedish-registry-real-world-data-feasibility Nationwide healthcare registries are potential important real-world data (RWD) sources for assessing drug effectiveness in oncology. However, it is unclear whether registry-… Fri, 12 Nov 2021 10:20:05 +0100 070333ff-0592-49ee-a921-196403024d5c Big data for big issues: Revealing travel patterns of low-income population based on smart card data mining in a global south unequal city https://www.lupop.lu.se/article/big-data-big-issues-revealing-travel-patterns-low-income-population-based-smart-card-data-mining Smart card data (SCD) allow analyzing mobility at a fine level of detail, despite the remaining challenges such as identifying trip purpose. The use of the SCD may improve the… Thu, 11 Nov 2021 10:19:55 +0100 1c385161-260a-4d8c-bbd5-5bdbb95f8c28 Development and Validation of a Large Synthetic Cohort for the Study of Cardiovascular Health Across the Life Span https://www.lupop.lu.se/article/development-and-validation-large-synthetic-cohort-study-cardiovascular-health-across-life-span We developed and validated a synthetic cohort approach to examine numbers of cardiovascular risk factors (CRFs) and adverse clinical events, including incident cardiovascular… Wed, 10 Nov 2021 10:20:08 +0100 64fefe40-f998-4c7f-b727-c3239888323b Effect of Adjustment for Case Misclassification and Infection Date Uncertainty on Estimates of COVID-19 Effective Reproduction Number https://www.lupop.lu.se/article/effect-adjustment-case-misclassification-and-infection-date-uncertainty-estimates-covid-19-effective Adjusting for epidemic curves based on surveillance data is necessary if estimates of missed cases and the effective reproduction number play a role in management of the COVID-19… Tue, 09 Nov 2021 10:20:06 +0100 aeaff88a-e766-4485-974f-b36b781caf6b Extension of Mendelian Randomization to Identify Earliest Manifestations of Alzheimer Disease https://www.lupop.lu.se/article/extension-mendelian-randomization-identify-earliest-manifestations-alzheimer-disease In an extension of Mendelian randomization, we leveraged variation in genetic risk for late-onset AD risk to estimate the causal effect of AD on BMI and the earliest ages at… Mon, 08 Nov 2021 10:20:04 +0100 211ae506-4200-4c11-a3e1-12636db25bd0 Marginal Sufficient Component Cause Model - An Emerging Causal Model With Merits? https://www.lupop.lu.se/article/marginal-sufficient-component-cause-model-emerging-causal-model-merits In this article, we illustrate that careful scrutiny based on the conventional sufficient cause model yields further insights into the concept of agonism in a more biologic sense. Mon, 08 Nov 2021 10:20:04 +0100 220c5a3a-1e41-446c-876b-b8eac71d050a On the use of nonparametric bounds for causal effects in null randomized trials https://www.lupop.lu.se/article/use-nonparametric-bounds-causal-effects-null-randomized-trials The Danish randomized trial studying the effect of mask recommendation (DANMASK-19) was widely discussed in the media. We aimed to analyze this trial from a causal inference… Sat, 06 Nov 2021 10:19:49 +0100 80dfee72-ce75-4bf5-a012-c1010f6a29c9 Strength in causality: discerning causal mechanisms in the sufficient cause model https://www.lupop.lu.se/article/strength-causality-discerning-causal-mechanisms-sufficient-cause-model In this article, we discuss how to discern the causal mechanisms of interest in the sufficient cause model, which pays closer attention to the relationship between the sufficient… Fri, 05 Nov 2021 10:19:52 +0100 3bff05b7-c725-4749-a855-a105a041c7c4 The Case Time Series Design https://www.lupop.lu.se/article/case-time-series-design The case time series design represents a general and flexible tool, applicable in different epidemiologic areas for investigating transient associations with environmental factors… Thu, 04 Nov 2021 10:19:57 +0100 22dc1d8c-78cb-4d09-ab0e-ef3b02283ddb The Causal Interpretation of “Overall Vaccine Effectiveness” in Test-Negative Studies https://www.lupop.lu.se/article/causal-interpretation-overall-vaccine-effectiveness-test-negative-studies In this article we discuss the potential for a weighted average of age-specific VE estimates to provide a more meaningful measure of overall VE. Wed, 03 Nov 2021 10:19:51 +0100 b4071cb6-fa1e-459b-b306-d5c60b12dcb7 Ny studie från Region Skåne: Återfall av Clostridium difficle https://www.lupop.lu.se/article/ny-studie-fran-region-skane-aterfall-av-clostridium-difficle Vid verksamhetsområdet infektionssjukdomar på Skånes universitetssjukhus planeras en studie kring återfall av Clostridium difficile (nyligen namnbyte till Clodstridoides difficile… Tue, 02 Nov 2021 07:52:35 +0100 de1e2953-adbf-4392-a031-b1a55e17a9df Nu kan du anmäla informationssäkerhetsincidenter! https://www.lupop.lu.se/article/nu-kan-du-anmala-informationssakerhetsincidenter Har du tappat bort ett USB-minne med känsliga uppgifter? Eller har du sett någon stryka omkring i universitetets lokaler med en möjlig avsikt att tillskansa sig värdefull… Fri, 29 Oct 2021 14:33:44 +0200 f8097ef8-3ff1-412e-81a4-607056c9e218 Digitalt informationsmöte om förändringar av Fortes årliga öppna utlysning https://www.lupop.lu.se/article/digitalt-informationsmote-om-forandringar-av-fortes-arliga-oppna-utlysning För den som missade seminariet om Fortes nya ansökningsregler finns det nu tillgängligt på nätet. Fri, 22 Oct 2021 07:57:17 +0200 267930a7-f715-4a9a-a586-f0d07ff70e34 Vetenskapsrådets samordningsuppdrag om öppen tillgång till forskningsdata – delredovisning https://www.lupop.lu.se/article/vetenskapsradets-samordningsuppdrag-om-oppen-tillgang-till-forskningsdata-delredovisning Vetenskapsrådet har i uppdrag av regeringen att främja och samordna det nationella arbetet med att införa öppen tillgång till forskningsdata. Denna rapport är en delredovisning av… Fri, 22 Oct 2021 07:36:54 +0200 3b760e61-0842-4cde-956d-51798c1b5eac New LU-policy for open access https://www.lupop.lu.se/article/new-lu-policy-open-access Open access (OA) means that research results are published freely available to everyone on the web. The university's open access policy is a way of contributing to open… Wed, 20 Oct 2021 12:41:28 +0200 afb4b514-5def-4f82-99f9-393908419be2 Registration now open for Lund Population Day 2021 https://www.lupop.lu.se/article/registration-now-open-lund-population-day-2021 Big microdata and population research, with keynote speaker Professor Steve Ruggles. Thu, 14 Oct 2021 09:04:13 +0200 b206f8f3-8e4e-4783-a82c-41e0919579e6 Job opportunity: Doctoral student in Medical Science - Environmental risk factors for IBD https://www.lupop.lu.se/article/job-opportunity-doctoral-student-medical-science-environmental-risk-factors-ibd Project title: Early-life environmental risk factors for inflammatory bowel disease: A Nordic birth cohort study Wed, 13 Oct 2021 09:35:55 +0200 ab553d3b-8b2a-427c-8de1-c65a42f889b9 SWE-REG Autumn Meeting 2021: How to conduct successful interdisciplinary research https://www.lupop.lu.se/article/swe-reg-autumn-meeting-2021-how-conduct-successful-interdisciplinary-research The Swedish Network for Register-Based Research (SWE-REG) is a collaboration between eight research nodes – seven research environments and a graduate school in register-based… Mon, 11 Oct 2021 11:15:13 +0200 a818ed5e-d735-4757-9cd7-44826de027cb Med fokus på jämlik bröstcancervård https://www.lupop.lu.se/article/med-fokus-pa-jamlik-brostcancervard En registerstudie om utvecklingen inom cancerrehabiliteringsområdet samt likheter och skillnader mellan migrerade och svenskfödda kvinnor - en ny studie från Lunds universitet Thu, 07 Oct 2021 08:53:45 +0200 c9b58b2b-14ae-4d2b-a551-c6c1b820f715 Hållbara utemiljöer: Systematiska, tvärvetenskapliga studier av hälsoeffekter och påverkan på sociala ojämlikheter baserad på Malmö Kost Cancer-kohorten. https://www.lupop.lu.se/article/hallbara-utemiljoer-systematiska-tvarvetenskapliga-studier-av-halsoeffekter-och-paverkan-pa-sociala Ny studie från Lunds universitet. Tue, 05 Oct 2021 09:53:09 +0200 8b8e60a2-6eb4-46e1-8f14-b9cc8f56560f Rounding up the usual suspects: confirmation bias in epidemiological research https://www.lupop.lu.se/article/rounding-usual-suspects-confirmation-bias-epidemiological-research Investigators performing epidemiological research frequently form hypotheses based on data availability. One might ask how it could be otherwise. After all, what is the point of… Sat, 25 Sep 2021 10:20:32 +0200 ed242835-1ee2-4bdb-bf52-2722d21e4a42 The use of negative control outcomes in Mendelian randomization to detect potential population stratification https://www.lupop.lu.se/article/use-negative-control-outcomes-mendelian-randomization-detect-potential-population-stratification A key assumption of Mendelian randomization (MR) analysis is that there is no association between the genetic variants used as instruments and the outcome other than through the… Fri, 24 Sep 2021 15:19:46 +0200 1a3a5736-b15d-4a68-ac5b-89f2faaacfed Bättre beslutsstöd för isolering av patienter med misstänkt COVID-19 på akutmottagningarna https://www.lupop.lu.se/article/battre-beslutsstod-isolering-av-patienter-med-misstankt-covid-19-pa-akutmottagningarna Ny studie från Lunds universitet, Karolinska Institutet och Region Skåne. Fri, 24 Sep 2021 14:20:59 +0200 77ddb920-1294-4bf9-afd5-9aac10bce220 Methodical considerations on adjusting for Charlson Comorbidity Index in epidemiological studies https://www.lupop.lu.se/article/methodical-considerations-adjusting-charlson-comorbidity-index-epidemiological-studies Confounding by comorbidities is of concern in many epidemiological studies. To take this into account a common strategy is to calculate each participant’s Charlson Comorbidity… Fri, 24 Sep 2021 10:19:58 +0200 f24bbb9a-c034-4d2a-b50a-6c21ef5d21ac Acceptability of patient reported outcome measures (PROMs) in a cystic fibrosis data registry https://www.lupop.lu.se/article/acceptability-patient-reported-outcome-measures-proms-cystic-fibrosis-data-registry Improvements in the treatment of cystic fibrosis (CF) have resulted in longer survival and an increased focus on optimising daily functioning with the condition. Patient-… Thu, 23 Sep 2021 15:19:48 +0200 29e72241-6021-436c-ae88-284dfde5c93e Parametric-Regression–Based Causal Mediation Analysis of Binary Outcomes and Binary Mediators: Moving Beyond the Rareness or Commonness of the Outcome https://www.lupop.lu.se/article/parametric-regression-based-causal-mediation-analysis-binary-outcomes-and-binary-mediators-moving In the causal mediation framework, several parametric-regression–based approaches have been introduced in the last decade for estimating natural direct and indirect effects. For a… Thu, 23 Sep 2021 10:20:03 +0200 cd36d5ee-df31-4056-bb11-9ec12a851eaf Matched Versus Unmatched Analysis of Matched Case-Control Studies https://www.lupop.lu.se/article/matched-versus-unmatched-analysis-matched-case-control-studies Although the need for addressing matching in the analysis of matched case-control studies is well established, debate remains as to the most appropriate analytical method when… Wed, 22 Sep 2021 15:19:51 +0200 a8618c0b-e28d-49c1-9f4f-6b2e12688ac6 Data-Driven Model Building for Life-Course Epidemiology https://www.lupop.lu.se/article/data-driven-model-building-life-course-epidemiology Life-course epidemiology is useful for describing and analyzing complex etiological mechanisms for disease development, but existing statistical methods are essentially… Wed, 22 Sep 2021 10:19:41 +0200 a56a3cfe-28c0-4372-8447-13e77a88d113 A Survivorship-Period-Cohort Model for Cancer Survival: Application to Liver Cancer in Taiwan, 1997–2016 https://www.lupop.lu.se/article/survivorship-period-cohort-model-cancer-survival-application-liver-cancer-taiwan-1997-2016 Monitoring survival in cancer is a common concern for patients, physicians, and public health researchers. The traditional cohort approach for monitoring cancer prognosis has a… Tue, 21 Sep 2021 15:19:47 +0200 9d458144-cb50-4e7a-967f-5de3df6bec99 Multiple-bias Sensitivity Analysis Using Bounds https://www.lupop.lu.se/article/multiple-bias-sensitivity-analysis-using-bounds Confounding, selection bias, and measurement error are well-known sources of bias in epidemiologic research. Methods for assessing these biases have their own limitations. Tue, 21 Sep 2021 10:20:02 +0200 7e19214e-1793-4cd4-b56f-a06323788a8a Decreased Susceptibility of Marginal Odds Ratios to Finite-sample Bias https://www.lupop.lu.se/article/decreased-susceptibility-marginal-odds-ratios-finite-sample-bias Parameters representing adjusted treatment effects may be defined marginally or conditionally on covariates. The choice between a marginal or covariate-conditional parameter… Mon, 20 Sep 2021 15:19:46 +0200 3ce96504-7fa6-437d-aed5-0dd124671e83 CARTR Plus: the creation of an ART registry in Canada https://www.lupop.lu.se/article/cartr-plus-creation-art-registry-canada The CARTR Plus registry is a robust resource for ART data in Canada. It provides easily accessible aggregated data for Canadian fertility clinics, and it contains data that are… Mon, 20 Sep 2021 10:19:39 +0200 9165ffd2-79d8-447c-8d9e-551b7175022d Esophageal resection in Austria—preparing a national registry https://www.lupop.lu.se/article/esophageal-resection-austria-preparing-national-registry This first publication of the Austrian Society of Esophageal Surgery shows that the outcome of esophageal surgery for cancer in Austria compares well with that of renowned… Sun, 19 Sep 2021 15:19:45 +0200 6c2d896e-29d6-4a64-8330-a5eb8df93013 Integrating Electronic Health Record, Cancer Registry, and Geospatial Data to Study Lung Cancer in Asian American, Native Hawaiian, and Pacific Islander Ethnic Groups https://www.lupop.lu.se/article/integrating-electronic-health-record-cancer-registry-and-geospatial-data-study-lung-cancer-asian The integrative data approach is an effective way to conduct cancer research assessing multilevel factors on cancer outcomes among small populations. Sun, 19 Sep 2021 10:19:41 +0200 32eefcca-fa2d-4a65-ab86-16d920df7618 Validating Acute Myocardial Infarction Diagnoses in National Health Registers for Use as Endpoint in Research: The Tromsø Study https://www.lupop.lu.se/article/validating-acute-myocardial-infarction-diagnoses-national-health-registers-use-endpoint-research The benefits of using data from national registers as endpoints in epidemiological studies include faster, less resource-intensive access to nationwide data and considerably lower… Sat, 18 Sep 2021 15:19:37 +0200 a2429076-b608-4083-a91e-344fdc28b588